IMPROVEMENT OF DIAGNOSTIC MEASURES FOR CHRONIC LIVER DAMAGE IN RATS

Authors

  • A. N. Aripov Republican Specialized Scientific and Practical Medical Center of Pediatrics of the Ministry of Health of the Republic of Uzbekistan
  • L. L. Akhunzhanova Republican Specialized Scientific and Practical Medical Center of Pediatrics of the Ministry of Health of the Republic of Uzbekistan
  • O. A. Aripov Republican Specialized Scientific and Practical Medical Center of Pediatrics of the Ministry of Health of the Republic of Uzbekistan
  • A. U. Nabiev Republican Specialized Scientific and Practical Medical Center of Pediatrics of the Ministry of Health of the Republic of Uzbekistan
  • B.B. Mukhammadzhonov Republican Specialized Scientific and Practical Medical Center of Pediatrics of the Ministry of Health of the Republic of Uzbekistan
  • Sh. B. Karimov Republican Specialized Scientific and Practical Medical Center of Pediatrics of the Ministry of Health of the Republic of Uzbekistan

Keywords:

Heliotrin, liver damage, liver fibrosis, chronic liver diseases, toxic hepatitis

Abstract

This article describes the work on the formation of a model of chronic liver diseases in the conditions of pathology research, which is considered relevant today. In this regard, in order to timely and effective treatment of chronic liver diseases, a number of research works are being carried out aimed at improving their diagnosis at early stages. In the conducted studies, death was observed in 30% of animals in the experimental group exposed to heliotrin, a substance with liver-damaging properties. At the same time, although the biochemical parameters of the blood also underwent significant changes, it was noticed that the platelet growth factor also increased in proportion to these signs.

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Published

2023-07-24