Assessment of Morphological Changes in the Kidneys Under the Impact of Energy Drinks

Abstract

This work is devoted to the study of the morphological state of the kidneys of rats under the influence of energy drinks on the body. The use of energy drinks can cause problems with the urinary system, the rapid depletion of the body's resources. Due to the use of energy drinks, they take a lot of energy from the body at once, which leads to the inevitable depletion of the nervous system, metabolic disorders. We have studied the morphofunctional state of the kidneys of outbred rats when exposed to an energy drink. The study was conducted on white bisexual rats weighing 125-137 g. The animals were divided into two groups: 1 - control group, 2 - experimental group of animals that received the drink in doses for 30 days. Experimental animals were on a general vivarious diet, a 12-hour light change. The slaughter was carried out by decapitation on the 30th day and the kidney was separated for histological examination. These studies were performed after standard histological examination and paraffin embedding and staining of sections with hematoxylin and eosin. Histological studies 30 days after the use of energy drinks in the experiment in the kidneys observed acellular fibrosis and hyalinosis of the stroma of the pyramid, an increase in the size of individual renal corpuscles, capillary glomeruli filled with blood, a thinned outer leaf of the capsule, and the cavity of the capsule is noticeably enlarged. In some renal bodies, processes of degenerative changes are observed. The epithelium of the proximal tubules becomes lower and the process of karyolysis is observed in some cells, dystrophic changes in the epithelium are observed in the distal tubules and collecting ducts . And, moderate ectasia of the collecting ducts, atrophy of the direct tubules and collecting ducts. Thus, the histological data obtained from the study of rat kidneys indicate that there is a high sensitivity of the kidneys to the effects of energy drinks.