A Modern Approach to the Correction of Lipid Metabolism in Kidney Disease
Keywords:
chronic kidney disease, cholesterol, triglycerides, low density lipoproteins, high density lipoproteins, apo AI, apo AII, lipoprotein lipase, hepatic triglyceride lipase, statins, fibrates, nicotinic acidAbstract
Chronic kidney disease — a proven risk factor of the development and progression of lipid metabolism disorders. The basis of these disorders — an increase in blood plasma cholesterol, triglycerides, low density lipoproteins and decreased levels of high density lipoproteins, apo AI and apo AII. There has been a decrease in the activity of enzymes: lipoprotein lipase, hepatic triglyceride lipase, lecithin-cholesterol acyltransferase. The use of lipid modifying drugs — statins, fibrates, nicotinic acid was proposed.